gDocsUploader is a nice little OS X application for easy bulk upload of office documents to Google Docs. gDocsUploader shines with some cool drag and drop options. I have the program icon setup on the Dock for easier access.

Windows Users have DocSyncer which supports syncing and mobile access. A Mac OS X version of DocSyncer is expected soon too.
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Here is a LifeHacker Commentary on this Post:-
http://lifehacker.com/382160/drag-and-drop-upload-files-to-google-docs-with-gdocsuploader
Another TUAW commentary:-
http://www.tuaw.com/2008/04/22/gdocsuploader-puts-google-docs-api-to-use/
You should be aware that a newer version has been released that also supports basic uploading of photos to Picasa Web Albums.